Welcome to the centrosome:db database:

Centrosome:db contains a set of human and fly genes encoding proteins that are localized in the centrosome, either as centrosome constituents or as centrosome visitors. Genes have been considered as centrosomal on the basis of different kinds of evidences including high-throughput proteomics assays, annotations in public databases and orthology relationships to centrosomal genes in closely related species (e.g. mouse). For each of these genes we have compiled information from various sources such as Ensembl, OMIM, HPRD, Flybase, SNPs, GeneOntology or Compara, among others. Orthologs in other species, ranging from yeast to mammals, have been also included in centrosome:db. The domain structure of all the associated peptides has been characterized based on the domain profiles of the Pfam and Superfamily databases and on the coiled-coil predictions of the COILS program. You can browse the database by:

Now you can also browse the database by searching for the fly genes!

How to cite us:

Alves-Cruzeiro, J., Nogales-Cadenas, R.; Pascual-Montano, A. CentrosomeDB: A new generation of the Centrosomal Proteins Database for Human and Drosophila melanogaster. Nucl. Acids Res. 2013 doi: 10.1093/nar/gkt1126.
[Medline] [Online version]

Nogales-Cadenas, R., Abascal, F., Díez-Pérez, J., Carazo, JM, Pascual-Montano, A. CentrosomeDB: A Human Centrosomal Proteins Database. Nucleic Acids Research 2008; doi: 10.1093/nar/gkn815
[Medline] [Online version]


This work is supported by a scientific project named CENTROSOME_CM (CAM - P2006/Gen-0166) granted by the Government of Madrid, Spain (CAM)

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